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Virus-Host Factor Interaction Database (VHFIDB) is a comprehensive and beneficial database which includes a wide array of host factors (essential and antiviral) associated with virus infections. This database encompasses detailed information regarding different host factors and their functions in respect of virus biology. The data has been keenly curated from the available published articles which focus on host factors identified through siRNA based gene knockdown approaches, CRISPR-cas based gene knockout approaches, etc. or by any other techniques.

Currently, VHFIDB contains thorough information about published articles, gene information and virus information for 9589 host factors of 72 virus species from 25 different virus families. Beside this most extensive coverage, VHFIDB is also hitched with five powerful analysis tool, namely, VHF pathogen network, VHF overlap analysis, VHF pathogen protein interacting analysis, gene enrichment analysis, and GWAS candidate gene analysis which increases the domain of VHFIDB.